Invitrogen™ KCNMB4 Monoclonal Antibody (1G7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA521735

Catalog No. PIMA521735

Description

Peptide Sequence: MAKLRVAYEY TEAEDKSIRL GLFLIISGVV SLFIFGFCWL SPALQDLQAT EANCTVLSVQ QIGEVFECTF TCGADCRGTS QYPCVQVYVN NSESNSRALL HSDEHQLLTN PKCSYIPPCK RENQKNLESV MNWQQYWKDE IGSQPFTCYF NQHQRPDDVL LHRTHDEIVL LHCFLWPLVT FVVGVLIVVL TICAKSLAVK AEAMKKRKFS.

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit.

Specifications

• Antigen: KCNMB4
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q86W47
• Gene Symbols: KCNMB4
• Immunogen: KCNMB4 (AAH50621, 1 a.a. ~ 210 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA
• Clone: 1G7
• Conjugate: Unconjugated
• Gene: KCNMB4
• Gene Alias: 1700058G18Rik; 2900045G12Rik; big potassium channel beta subunit 4; BK channel beta subunit 4; BK channel subunit beta-4; BKbeta4; calcium activated potassium channel beta 4 subunit; calcium-activated potassium channel subunit beta-4; Calcium-activated potassium channel, subfamily M subunit beta-4; charybdotoxin receptor subunit beta-4; hbeta4; k(VCA)beta-4; KCMB4; KCNMB4; large conductance calcium-dependent potassium ion channel beta 4 subunit; maxi K channel subunit beta-4; MaxiK channel beta-subunit 4; potassium calcium-activated channel subfamily M regulatory beta subunit 4; potassium channel subfamily M regulatory beta subunit 4; potassium large conductance calcium-activated channel, subfamily M, beta member 4; slo-beta-4; Slowpoke beta 4
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27345
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid