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Invitrogen™ KCNN2 Polyclonal Antibody
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Catalog No. PIPA541012
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100 μL
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PIPA541012 100 μL
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Catalog No. PIPA541012 Supplier Invitrogen™ Supplier No. PA541012
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Description

Rabbit Polyclonal Antibody

Peptide sequence: IDHAKVRKHQ RKFLQAIHQL RSVKMEQRKL NDQANTLVDL AKTQNIMYDM Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Yeast: 100%; Zebrafish: 93%.

Action potentials in vertebrate neurons are followed by an afterhyperpolarization that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KCNN2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene Kcnn2
Gene Accession No. P70604, Q9H2S1
Gene Alias apamin-sensitive small-conductance Ca2+-activated potassium channel; fri; hSK2; KCa2.2; KCNN2; potassium calcium-activated channel subfamily N member 2; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2; potassium intermediate/small conductance calcium-activated channel type2; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; SK2; SKCa 2; SKCa2; small conductance calcium-activated channel, subfamily N, member 2; small conductance calcium-activated potassium channel 2; small conductance calcium-activated potassium channel protein 2; small conductance calcium-activated potassium channel protein 2-like; small conductance calcium-activated potassium channel subfamily N member 2; small conductance potassium channel type 2; small conductance potassium channel type2; small conductance potassium channel type2 variant2
Gene Symbols Kcnn2
Host Species Rabbit
Immunogen Synthetic peptide directed towards the C-terminal of human KCNN2 (aa 443-492).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3781, 54262
Target Species Human, Rat, Monkey
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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