KCNN3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-1432	Proteintech Group Inc 171881AP150UL	150 μL

Description

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.

Specifications

• Antigen: KCNN3
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P58391, P70605, Q9UGI6
• Gene ID (Entrez): 140493, 3782, 54263
• Immunogen: KCNN3 Fusion Protein Ag10972
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: KCNN3

• Concentration: 0.21 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: hSK3, K3, KCa2.3, KCNN3, SK3, SKCa 3, SKCA3
• Gene Symbols: KCNN3
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody