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KCNQ2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981617
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50-198-1617 100 μL
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Catalog No. 50-198-1617 Supplier Bioss Supplier No. BS11728R
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Description

Rabbit Polyclonal Antibody

KCNQs are members of the voltage-dependent non-inactivating potassium channel family. Currently there are five known KNCQs (KCNQ1-5) found in the central nervous system and KNCQ2 and 3 have demonstrated their importance in M-current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M-current. Inhibition of M-current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy.

Specifications

Antigen KCNQ2
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene KCNQ2
Gene Accession No. O43526
Gene Alias BFNC; EBN; EBN1; ENB1; HNSPC; KCNA11; KCNQ2; KQT like 2; Kqt2; KQT-like 2; KV7.2; KVEBN1; mKQT2.3; mKQT2.4; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Nmf134; Potassium channel subunit alpha KvLQT2; potassium channel, voltage gated KQT-like subfamily Q, member 2; potassium channel, voltage-gated KQT-like subfamily Q, member 2; potassium voltage-gated channel KQT-like subfamily member 2.3; potassium voltage-gated channel KQT-like subfamily member 2.4; Potassium voltage-gated channel subfamily KQT member 2; potassium voltage-gated channel subfamily Q member 2; potassium voltage-gated channel, KQT-like subfamily, member 2; potassium voltage-gated channel, subfamily Q, member 2; Voltage-gated potassium channel subunit Kv7.2
Gene Symbols KCNQ2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human KCNQ2 .
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3785
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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