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KCNQ3 Rabbit anti-Human, Porcine, Polyclonal, Proteintech
SDP

Catalog No. 501732629 Shop All Proteintech Group Inc Products
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50-173-2629 150 μL
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Catalog No. 50-173-2629 Supplier Proteintech Group Inc Supplier No. 199661AP150UL
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Description

Rabbit Polyclonal Antibody

The antibody recognizes the C-term of KCNQ3.

KCNQs are members of the voltage-dependent non-inactivating potassium channel family. Currently there are five known KCNQs (KCNQ1-5) found in the central nervous system and KCNQ2 and 3 have demonstrated their importance in M-current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M-current. Inhibition of M-current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy.

Specifications

Antigen KCNQ3
Applications Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene KCNQ3
Gene Accession No. O43525
Gene Alias BFNC2, EBN2, KCNQ3, KQT like 3, KV7.3
Gene Symbols KCNQ3
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100157152, 3786
Target Species Human, Pig
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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