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Invitrogen™ KCNQ4 Polyclonal Antibody
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Catalog No. PIPA518812
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100 μg
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Catalog No. Quantity
PIPA518812 100 μg
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Catalog No. PIPA518812 Supplier Invitrogen™ Supplier No. PA518812
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Description

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.

The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2, an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KCNQ4
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene KCNQ4
Gene Accession No. P56696
Gene Alias DFNA 2; DFNA2; DFNA2A; KCNQ 4; KCNQ4; KQT like 4; KQT-like 4; KV7.4; LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily KQT member 4; potassium channel KQT-like 4; potassium channel subunit alpha KvLQT4; potassium channel, voltage gated KQT-like subfamily Q, member 4; potassium channel, voltage-gated KQT-like subfamily Q, member 4; potassium voltage-gated channel KQT-like protein 4; potassium voltage-gated channel KQT-like subfamily member 4; potassium voltage-gated channel subfamily KQT member 4; potassium voltage-gated channel subfamily Q member 4; potassium voltage-gated channel, KQT-like subfamily, member 4; potassium voltage-gated channel, subfamily Q, member 4; voltage-gated potassium channel subunit Kv7.4
Gene Symbols KCNQ4
Host Species Goat
Immunogen Synthetic peptide sequence (DKGPSDAEVVDE) corresponding to the internal amino acids of KCNQ4 (aa 601-613).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9132
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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