Invitrogen™ KCNT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599644

Catalog No. PIPA599644

Description

Antibody detects endogenous levels of total KCNT1.

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: KCNT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Kcnt1
• Gene Alias: bA100C15.2; C030030G16Rik; EIEE14; ENFL5; KCa4.1; KCa4.1KIAA1422FLJ41282; Kcnt1; KIAA1422; Potassium channel subfamily T member 1; potassium channel subunit (Slack); potassium channel, sodium activated subfamily T, member 1; potassium channel, sodium-activated subfamily T, member 1; potassium channel, subfamily T, member 1; potassium sodium-activated channel subfamily T member 1; rSlo2; Sequence like a calcium-activated K+ channel; sequence like a calcium-activated potassium channel subunit; Slack; slo2; Slo2.2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 227632, 57582, 60444
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q5JUK3, Q6ZPR4, Q9Z258
• Gene Symbols: Kcnt1
• Immunogen: A synthesized peptide derived from human KCNT1(Accession Q5JUK3), corresponding to amino acid residues I1019-G1069.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG