KCNT2 Monoclonal Antibody (S11-33), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA527590

Catalog No. PIMA527590

Description

Kcnt2 calcium (Ca2+) -activated potassium channels (KCa) are a group of 6/7-TM ion channels that selectively transport K+ ions across biological membranes. KCa channels are broadly classified into three subtypes: SK, IK and BK channels (small, intermediate and big conductance). Kcnt2 is an outward rectifying potassium channel, and produces rapidly activating outward rectifier K(+) currents. Kcnt2 is activated by high intracellular sodium and chloride levels. Further, Kcnt2 channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane. Functionally, Kcnt2 is inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1.

Specifications

• Antigen: KCNT2
• Classification: Monoclonal
• Concentration: 1 mg/ml
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q6UVM3, Q6UVM4
• Gene Symbols: KCNT2
• Immunogen: Fusion protein amino acids 564-624 of mouse Slo2.1 (Slick)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: S11-33
• Conjugate: Unconjugated
• Gene: KCNT2
• Gene Alias: KCNT2, KCa4.2, SLICK, Slo2.1, sodium and chloride activated ATP sensitive potassium channel Slo2.1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 240776, 304827, 343450
• Content And Storage: -20°C
• Form: Liquid