KCNT2 Monoclonal Antibody (S11-33), Invitrogen™

Catalog No.	Quantity
PIMA527590	100 μg

Catalog No. PIMA527590

Supplier: Thermo Scientific MA527590

Description

Mouse Monoclonal Antibody

Kcnt2 calcium (Ca2+) -activated potassium channels (KCa) are a group of 6/7-TM ion channels that selectively transport K+ ions across biological membranes. KCa channels are broadly classified into three subtypes: SK, IK and BK channels (small, intermediate and big conductance). Kcnt2 is an outward rectifying potassium channel, and produces rapidly activating outward rectifier K(+) currents. Kcnt2 is activated by high intracellular sodium and chloride levels. Further, Kcnt2 channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane. Functionally, Kcnt2 is inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1.

Specifications

• Antigen: KCNT2
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: S11-33
• Concentration: 1 mg/ml
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
• Gene: KCNT2
• Gene Accession No.: Q6UVM3, Q6UVM4
• Gene Alias: KCNT2, KCa4.2, SLICK, Slo2.1, sodium and chloride activated ATP sensitive potassium channel Slo2.1
• Gene Symbols: KCNT2
• Host Species: Mouse
• Immunogen: Fusion protein amino acids 564-624 of mouse Slo2.1 (Slick)
• Purification Method: Protein G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 240776, 304827, 343450
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1