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Invitrogen™ KCTD11 Polyclonal Antibody
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Catalog No. PIPA562539
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100 μL
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PIPA562539 100 μL
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Catalog No. PIPA562539 Supplier Invitrogen™ Supplier No. PA562539
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DALRELEASQ GTPAPTAALL HADVDVSPRL VHFSARRGPH HYELSSVQVD TFRANLFCTD SECLGALRAR FGVAS Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 92%.

Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers. It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KCTD11
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene KCTD11
Gene Accession No. Q693B1
Gene Alias AF465352; BTB/POZ domain-containing protein KCTD11; C17orf36; KCASH1; KCASH1 protein; KCTD11; potassium channel tetramerisation domain containing 11; potassium channel tetramerization domain containing 11; potassium channel tetramerization domain-containing protein 11; REN; REN/KCTD11; retinoic acid, EGF, and NGF upregulated; retinoic acid, EGF, NGF induced gene protein; retinoic acid, EGF, NGF induced gene/potassium channel tetramerization domain containing 11; RING-type E3 ubiquitin transferase KCTD11; RING-type E3 ubiquitin transferase subunit KCTD11
Gene Symbols KCTD11
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human KCTD11. Recombinant protein control fragment (Product #RP-100331).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 147040
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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