Invitrogen™ KCTD13 Monoclonal Antibody (OTI3B12)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527056

Catalog No. PIMA527056

Description

KCTD13 Monoclonal Antibody for Western Blot, IHC (P)

Cytochrome P450 super family proteins are monooxygenases which catalyze multiple biochemical reactions involved in drug metabolism and synthesis of cholesterol, steroids and lipids. CYP4F3, a 60KDa protein, is a novel member of this family. It consists of a conserved heme-binding domain near the C-terminus and catalyzes the u-hydroxylation of LTB4. CYP4F3 is localized in the ER and plays a vital role in the inactivation of LTB4 and controlling inflammation. CYP4F3 exists in two functionally distinct isoforms: CYP4F3A, a neutrophil isoform, is particularly expressed in neutrophils and myeloid cells and catalyzes the microsomal u-hydroxylation of LTB4. It interacts with CD11b and myeloperoxidase on myeloid cells and regulates cellular development in bone marrow. CYP4F3B, a liver isoform, catalyzes the conversion of arachidonic acid to 20-HETE, a potent activator of PKC. Itrole hasbeen implicatedin cell proliferation, vascular tone and natriuresis.

Specifications

• Antigen: KCTD13
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8WZ19
• Gene Symbols: KCTD13
• Immunogen: Full length human recombinant protein of KCTD13 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI3B12
• Conjugate: Unconjugated
• Gene: KCTD13
• Gene Alias: 1500003N18Rik; AV259508; BACURD1; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1; BTB/POZ domain-containing protein KCTD13; CTD-2574D22.4; FKSG86; hBACURD1; Kctd13; PDIP1; PDIP1alpha; Poldip1; Polymerase delta-interacting protein 1; potassium channel tetramerisation domain containing 13; potassium channel tetramerization domain containing 13; PP6832; TNFAIP1-like protein; tumor necrosis factor alpha-inducible protein PDIP1; Unknown (protein for MGC:134443)
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 253980
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid