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Invitrogen™ KCTD13 Monoclonal Antibody (OTI3B12)
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Catalog No. PIMA527056
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100 μL
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PIMA527056 100 μL
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Catalog No. PIMA527056 Supplier Invitrogen™ Supplier No. MA527056
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Description

Mouse Monoclonal Antibody

KCTD13 Monoclonal Antibody for Western Blot, IHC (P)

Cytochrome P450 super family proteins are monooxygenases which catalyze multiple biochemical reactions involved in drug metabolism and synthesis of cholesterol, steroids and lipids. CYP4F3, a 60KDa protein, is a novel member of this family. It consists of a conserved heme-binding domain near the C-terminus and catalyzes the u-hydroxylation of LTB4. CYP4F3 is localized in the ER and plays a vital role in the inactivation of LTB4 and controlling inflammation. CYP4F3 exists in two functionally distinct isoforms: CYP4F3A, a neutrophil isoform, is particularly expressed in neutrophils and myeloid cells and catalyzes the microsomal u-hydroxylation of LTB4. It interacts with CD11b and myeloperoxidase on myeloid cells and regulates cellular development in bone marrow. CYP4F3B, a liver isoform, catalyzes the conversion of arachidonic acid to 20-HETE, a potent activator of PKC. Itrole hasbeen implicatedin cell proliferation, vascular tone and natriuresis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KCTD13
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI3B12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene KCTD13
Gene Accession No. Q8WZ19
Gene Alias 1500003N18Rik; AV259508; BACURD1; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1; BTB/POZ domain-containing protein KCTD13; CTD-2574D22.4; FKSG86; hBACURD1; Kctd13; PDIP1; PDIP1alpha; Poldip1; Polymerase delta-interacting protein 1; potassium channel tetramerisation domain containing 13; potassium channel tetramerization domain containing 13; PP6832; TNFAIP1-like protein; tumor necrosis factor alpha-inducible protein PDIP1; Unknown (protein for MGC:134443)
Gene Symbols KCTD13
Host Species Mouse
Immunogen Full length human recombinant protein of KCTD13 produced in E.coli.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 253980
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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