KCTD13 Monoclonal Antibody (OTI3B5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA808833

Catalog No. 50-168-2404

Description

Cytochrome P450 super family proteins are monooxygenases which catalyze multiple biochemical reactions involved in drug metabolism and synthesis of cholesterol, steroids and lipids. CYP4F3, a 60KDa protein, is a novel member of this family. It consists of a conserved heme-binding domain near the C-terminus and catalyzes the u-hydroxylation of LTB4. CYP4F3 is localized in the ER and plays a vital role in the inactivation of LTB4 and controlling inflammation. CYP4F3 exists in two functionally distinct isoforms: CYP4F3A, a neutrophil isoform, is particularly expressed in neutrophils and myeloid cells and catalyzes the microsomal u-hydroxylation of LTB4. It interacts with CD11b and myeloperoxidase on myeloid cells and regulates cellular development in bone marrow. CYP4F3B, a liver isoform, catalyzes the conversion of arachidonic acid to 20-HETE, a potent activator of PKC. Itrole hasbeen implicatedin cell proliferation, vascular tone and natriuresis.

Specifications

• Antigen: KCTD13
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q8WZ19
• Gene Symbols: KCTD13
• Immunogen: Full length human recombit protein of human KCTD13 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: OTI3B5
• Conjugate: Unconjugated
• Gene: KCTD13
• Gene Alias: BACURD1, FKSG86, PDIP1, POLDIP1, hBACURD1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 253980
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid