KCTD13 Mouse anti-Human, Clone: OTI7D5, lyophilized, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene CF808803
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCOCytochrome P450 super family proteins are monooxygenases which catalyze multiple biochemical reactions involved in drug metabolism and synthesis of cholesterol, steroids and lipids. CYP4F3, a 60KDa protein, is a novel member of this family. It consists of a conserved heme-binding domain near the C-terminus and catalyzes the u-hydroxylation of LTB4. CYP4F3 is localized in the ER and plays a vital role in the inactivation of LTB4 and controlling inflammation. CYP4F3 exists in two functionally distinct isoforms: CYP4F3A, a neutrophil isoform, is particularly expressed in neutrophils and myeloid cells and catalyzes the microsomal u-hydroxylation of LTB4. It interacts with CD11b and myeloperoxidase on myeloid cells and regulates cellular development in bone marrow. CYP4F3B, a liver isoform, catalyzes the conversion of arachidonic acid to 20-HETE, a potent activator of PKC. Itrole hasbeen implicatedin cell proliferation, vascular tone and natriuresis.
|Full length human recombit protein of human KCTD13 produced in E.coli.|
|PBS with 8% trehalose and no preservative; pH 7.3|
|BACURD1, FKSG86, PDIP1, POLDIP1, hBACURD1|
|-20° C, Avoid Freeze/Thaw Cycles|
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