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KDEL ER Marker Rabbit anti-Human, Polyclonal, Bioss
SDP

Rabbit Polyclonal Antibody

Supplier:  Bioss BS6940R

Encompass_Preferred

Catalog No. 50-198-7614


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Description

Description

The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins, GRP78 and GRP94 respectively, and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
Specifications

Specifications

KDEL ER Marker
Polyclonal
Unconjugated
HSPA5
78 kDa glucose-regulated protein; 8030486F04Rik; 94 kDa glucose-regulated protein; 94 kDa glucose-regulated protein {ECO:0000250; AL022860; AU019543; AW215843; baffled; Binding-immunoglobulin protein; BiP; D2Wsu141e; D2Wsu17e; ECGP; Endoplasmic reticulum chaperone BiP; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Endoplasmic reticulum resident protein 99; Endoplasmin; endoplasmin {ECO:0000250; endothelial cell (HBMEC) glycoprotein; epididymis luminal protein 35; epididymis secretory sperm binding protein Li 125m; epididymis secretory sperm binding protein Li 89n; ER lumen protein retaining receptor 1; ER lumen protein-retaining receptor 1; ERD2; ERD2.1; ERp99; glucose regulated protein, 78 kDa; glucose-regulated protein; glucose-regulated protein, 78kDa; GP96; gp96 homolog; GRP 78; Grp78; GRP-78; Grp94; GRP-94; HDEL; heat shock 70 kDa protein 5; heat shock 70kD protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock 70kDa protein 5 (glucose-regulated protein); heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); heat shock protein 5; Heat shock protein 70 family protein 5; heat shock protein 90 beta family member 1; Heat shock protein 90 kDa beta member 1; heat shock protein 90 kDa beta member 1 {ECO:0000250; heat shock protein 90, beta (Grp94), member 1; heat shock protein 90, beta, member 1; heat shock protein 90kDa beta (Grp94), member 1; heat shock protein 90kDa beta family member 1; heat shock protein family A (Hsp70) member 5; Heat shock protein family A member 5; HEL35; HEL-S-125m; HEL-S-89n; Hsce70; HSP70 family protein 5; HSP90B1; hsp90b1 {ECO:0000250; Hspa5; I79_019946; I79_020931; Immunoglobulin heavy chain-binding protein; KDEL; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1; KDEL endoplasmic reticulum protein retention receptor 1; KDEL receptor 1; Kdelr1; Lys-Asp-Glu-Leu; mBiP; MIF2; PM23; Polymorphic tumor rejection antigen 1; Putative MAPK-activating protein PM23; RP23-446N16.1; Sez7; SEZ-7; Steroidogenesis-activator polypeptide; stress-inducible tumor rejection antigen gp96; TA-3; Targ2; Tra1; Tra-1; transforming growth factor alpha regulated gene 2; tumor rejection antigen (gp96) 1; Tumor rejection antigen 1; Tumor rejection antigen gp96; UniProtKB:P08113}; XAP-1 antigen
Rabbit
Protein A
RUO
10945, 3309, 7184
-20°C
Liquid
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
P11021, P14625, P24390
Hsp90b1, HSPA5, Kdelr1
KLH conjugated synthetic peptide KDEL.
100 μL
Primary
Human
Antibody
IgG
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