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Invitrogen™ KDELR3 Polyclonal Antibody
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Catalog No. PIPA599316
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PIPA599316 100 μL
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Catalog No. PIPA599316 Supplier Invitrogen™ Supplier No. PA599316
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total KDELR3.

This gene encodes a member of the KDEL endoplasmic reticulum protein retention receptor family. Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR3 was the third member of the family to be identified. Alternate splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KDELR3
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene KDELR3
Gene Accession No. O43731, Q8R1L4
Gene Alias AI173274; ER lumen protein retaining receptor 3; ER lumen protein-retaining receptor 3; ERD23; ERD2L3; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3; KDEL endoplasmic reticulum protein retention receptor 3; KDEL receptor 3; Kdelr3
Gene Symbols KDELR3
Host Species Rabbit
Immunogen A synthesized peptide derived from human KDELR3(Accession O43731), corresponding to amino acid residues V62-S112.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 105785, 11015
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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