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KDM5B Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987076
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50-198-7076 100 μL
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Catalog No. 50-198-7076 Supplier Bioss Supplier No. BS6139R
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Description

Rabbit Polyclonal Antibody

KDM5B is a histone demethylase that demethylates ′Lys-4′ of histone H3, thereby playing a central role in histone code. It does not demethylate histone H3 ′Lys-9′ or H3 ′Lys-27′. KDM5B demethylates trimethylated, dimethylated and monomethylated H3 ′Lys-4′. It acts as a transcriptional corepressor for FOXG1B and PAX9. It favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, KDM5B may act as a tumor suppressor for melanoma.

Specifications

Antigen KDM5B
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene KDM5B
Gene Accession No. Q9UGL1
Gene Alias 2010009J12Rik; 2210016I17Rik; AW556288; Cancer/testis antigen 31; CT31; D1Ertd202e; Histone demethylase JARID1B; Jarid1b; jumonji, AT rich interactive domain 1B; jumonji, AT rich interactive domain 1B (Rbp2 like); Jumonji, AT rich interactive domain 1B (RBP2-like); Jumonji/ARID domain-containing protein 1B; Kdm5b; Kiaa4034; lysine (K)-specific demethylase 5B; lysine demethylase 5B; Lysine-specific demethylase 5B; mKIAA4034; Plu1; PLU-1; PPP1R98; protein phosphatase 1, regulatory subunit 98; PUT1; putative DNA/chromatin binding motif; putative DNA/chromatin binding motif 1; Rb-Bp2; RBBP2H1; RBBP2H1A; RBP2-H1; Retinoblastoma-binding protein 2 homolog 1; retinoblastoma-binding protein 2, homolog 1A; RGD1565602
Gene Symbols KDM5B
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human KDM5B/Jarid1B.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10765
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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