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KDM5C Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501729442 Shop All Proteintech Group Inc Products
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50-172-9442 150 μL
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Catalog No. 50-172-9442 Supplier Proteintech Group Inc Supplier No. 144261AP150UL
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Description

Rabbit Polyclonal Antibody

Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1.; Isoform 4 can activate the JNK pathway. Involved in the regulation of actin cytoskeleton reorganization, cell-matrix adhesion, cell-cell adhesion and cell migration.

Specifications

Antigen KDM5C
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.17 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene KDM5C
Gene Accession No. P41229, P41230
Gene Alias DXS1272E, Histone demethylase JARID1C, JARID1C, KDM5C, lysine (K) demethylase 5C, Lysine specific demethylase 5C, MRXJ, MRXSJ, Protein SmcX, Protein Xe169, SMCX, XE169
Gene Symbols Kdm5c
Host Species Rabbit
Immunogen KDM5C Fusion Protein Ag5791
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20591, 317432, 8242
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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