KDR Monoclonal Antibody (OTI12C1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA802572

Catalog No. 50-167-9307

Description

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Specifications

• Antigen: KDR
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P35968
• Gene Symbols: KDR
• Immunogen: Human recombit protein fragment corresponding to amino acids 786-1356 of human KDR produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot
• Clone: OTI12C1
• Conjugate: Unconjugated
• Gene: KDR
• Gene Alias: CD309, FLK1, VEGFR, VEGFR2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3791
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid