KDR Mouse anti-Human, Clone: OTI12C1, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF802572

Catalog No. 50-166-6057

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Specifications

• Antigen: KDR
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: KDR
• Gene Alias: CD309, FLK1, VEGFR, VEGFR2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3791
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI12C1
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P35968
• Gene Symbols: KDR
• Immunogen: Human recombit protein fragment corresponding to amino acids 786-1356 of human KDR produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a