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Invitrogen™ KEAP1 Monoclonal Antibody (7G4B10)
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Catalog No. PIMA517107
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100 μg
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Catalog No. Quantity
PIMA517107 100 μg
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Catalog No. PIMA517107 Supplier Invitrogen™ Supplier No. MA517107
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Description

Mouse Monoclonal Antibody

MA5-17107 targets KEAP1 in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human samples. The MA5-17107 immunogen is purified recombinant fragment of human KEAP1 (amino acids: 380-624 ) expressed in E. Coli. MA5-17107 detects KEAP1 which has a predicted molecular weight of approximately 69.7kDa.

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KEAP1
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 7G4B10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene Keap1
Gene Accession No. Q14145
Gene Alias cytosolic inhibitor of Nrf2; INrf2; Keap1; kelch like ECH associated protein 1; Kelch-like ECH-associated protein 1; kelch-like family member 19; kelch-like protein 19; Kiaa0132; KLHL19; mKIAA0132; NRF2 cytosolic inhibitor; ring canal protein
Gene Symbols Keap1
Host Species Mouse
Immunogen Purified recombinant fragment of human KEAP1 (amino acids: 380-624 ) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9817
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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