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Invitrogen™ KEAP1 Polyclonal Antibody
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Catalog No. PIPA534454
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100 μg
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Catalog No. Quantity
PIPA534454 100 μg
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Catalog No. PIPA534454 Supplier Invitrogen™ Supplier No. PA534454
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Description

Rabbit Polyclonal Antibody

A suggested positive control is human lung tissue lysate. PA5-34454 can be used with blocking peptide PEP-1496. The PA5-34454 immunogen is located within the last 50 amino acids of KEAP1. Predicted molecular ~ 70kD. In Western blot applications, this antibody has been observed to detect a band at: 65-70kD. Predicted species reactivity based on immunogen sequence: Pig: (100%).

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KEAP1
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Keap1
Gene Accession No. P57790, Q14145, Q9Z2X8
Gene Alias cytosolic inhibitor of Nrf2; INrf2; Keap1; kelch like ECH associated protein 1; Kelch-like ECH-associated protein 1; kelch-like family member 19; kelch-like protein 19; Kiaa0132; KLHL19; mKIAA0132; NRF2 cytosolic inhibitor; ring canal protein
Gene Symbols Keap1
Host Species Rabbit
Immunogen A peptide near the carboxy terminus of human KEAP1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117519, 50868, 9817
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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