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Invitrogen™ KEAP1 Recombinant Rabbit Monoclonal Antibody (PSH0-90)
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Catalog No. FERMA549609
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FERMA549609 100 μL
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Catalog No. FERMA549609 Supplier Invitrogen™ Supplier No. MA549609
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Description

Rabbit Recombinant Monoclonal Antibody

Sequence Similarities: 98% Mouse/Rat. Tissue Specificity: Broadly expressed, with highest levels in skeletal muscle. Positive Control: HepG2 cell lysate, HeLa cell lysate, MCF7 cell lysate, A431 cell lysate, Jurkat cell lysate, HEK-293 cell lysate, Daudi cell lysate, A549 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse kidney tissue, rat kidney tissue, PC-12. Subcellular Location: Cytoplasm, Nucleus. Predicted band size: 70 kDa.

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KEAP1
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone PSH0-90
Concentration 1.07 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Keap1
Gene Accession No. P57790, Q14145, Q9Z2X8
Gene Alias cytosolic inhibitor of Nrf2; INrf2; Keap1; kelch like ECH associated protein 1; Kelch-like ECH-associated protein 1; kelch-like family member 19; kelch-like protein 19; Kiaa0132; KLHL19; mKIAA0132; NRF2 cytosolic inhibitor; ring canal protein
Gene Symbols Keap1
Host Species Rabbit
Immunogen Recombinant protein within human KEAP1 aa 275-624.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117519, 50868, 9817
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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