Invitrogen™ Ketoprofen Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA175229

Catalog No. PIPA175229

Description

Working Concentration: 1.25 μg/mL. Sensitivity: 10 ng/mL Ketoprofen produces 28% inhibition in a competitive ELISA employing Ketoprofen polyclonal antibody.

Ketoprofen is only found in individuals that have used or taken this drug. It is a propionic acid derivative and is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties. The anti-inflammatory effects of ketoprofen are believed to be due to inhibition cylooxygenase-2 (COX-2), an enzyme involved in prostaglandin synthesis via the arachidonic acid pathway. This results in decreased levels of prostaglandins that mediate pain, fever and inflammation. Ketoprofen is a non-specific cyclooxygenase inhibitor and inhibition of COX-1 is thought to confer some of its side effects, such as GI upset and ulceration. Ketoprofen is thought to have anti-bradykinin activity, as well as lysosomal membrane-stabilizing action. Antipyretic effects may be due to action on the hypothalamus, resulting in an increased peripheral blood flow, vasodilation, and subsequent heat dissipation. [National Center for Biotechnology Information. PubChem Compound Database; CID=3825].

Specifications

• Antigen: Ketoprofen
• Classification: Polyclonal
• Formulation: PBS with 0.09% sodium azide; pH 7.3
• Host Species: Sheep
• Purification Method: purified
• Regulatory Status: RUO
• Target Species: Chemical
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA
• Conjugate: Unconjugated
• Gene Alias: C16H14O3
• Immunogen: Ketoprofen-BTG.
• Quantity: 1 mg
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid
• Target Molecule: Chemical

Safety and Handling

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