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Tocris Bioscience™ Ki 20227
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Catalog No. 448110
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44-811-0 10 mg
44-815-0 50 mg
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Catalog No. 44-811-0 Supplier Tocris Bioscience™ Supplier No. 4481/10
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Description

c-Fms inhibitor; suppresses osteolysis and osteoclast accumulation

Inhibitor of c-Fms tyrosine kinase (M-CSFR, CSF1R) (IC50 values are 2, 12, 217 and 451 nM for c-Fms, VEGFR-2, PDGFRβ and c-Kit respectively). Does not inhibit Flt3, EGFR or c-Src. Suppresses osteoclast differentiation and osteolysis in a rat bone metastasis model.

Chemical Identifiers

CAS 623142-96-1
Molecular Formula C24H24N4O5S

Specifications

Quantity 10 mg
Formula Weight 480.54
Purity >97%
Molecular Weight (g/mol) 480.539
Chemical Name or Material Ki 20227

Safety and Handling

Recommended Storage Store at +4°C
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