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Ki-67 Mouse anti-Human, Mouse, RB545, Clone: B56, BD Horizon™

Catalog No. BDB569276 Shop All BD Biosciences Products
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BDB569276 25 Tests
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Catalog No. BDB569276 Supplier BD Biosciences Supplier No. 569276
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Description

Mouse Monoclonal Antibody

The B56 monoclonal antibody specifically binds to the Ki-67 antigen that is expressed in the nucleus of cycling cells (G1, S, G2, M cell cycle phases). During the G0 phase, the antigen cannot be detected. During interphase of the cell cycle, it is associated with nucleolar components, and it is on the surface of the chromosomes during M phase. Ki-67 is a large protein having 2 alternatively spliced isoforms, an N-terminal forkhead-associated domain, a C-terminal domain that binds to heterochromatin proteins, and multiple phosphorylation sites, the functions of which are still unclear. Because of the strict association of Ki-67 expression with cell proliferation, anti-Ki-67 antibodies are useful for the identification, quantification, and monitoring of growing cell populations.

Ki-67 Monoclonal antibody specifically detects Ki-67 in Human, Mouse samples. It is validated for Intracellular Staining (Flow Cytometry)
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ki-67
Applications Flow Cytometry
Classification Monoclonal
Clone B56
Conjugate RB545
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias MKI67; Antigen identified by monoclonal antibody Ki-67; KIA
Host Species Mouse
Immunogen Human Ki-67
Purification Method Affinity Purified
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4288
Target Species Human, Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Form Purified
Isotype IgG1 κ
Excitation/Emission Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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