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BD Horizon™ Ki-67 Mouse, anti-Human, RY586, Clone: B56, BD Horizon™
Mouse Monoclonal Antibody
Supplier: BD Horizon™ 568147
This item is not returnable.
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Description
The B56 monoclonal antibody specifically binds to the Ki-67 antigen that is expressed in the nucleus of cycling cells (G1, S, G2, M cell cycle phases). During the G0 phase, the antigen cannot be detected. During interphase of the cell cycle, it is associated with nucleolar components, and it is on the surface of the chromosomes during M phase. Ki-67 is a large protein having 2 alternatively spliced isoforms, an N-terminal forkhead-associated domain, a C-terminal domain that binds to heterochromatin proteins, and multiple phosphorylation sites, the functions of which are still unclear. Because of the strict association of Ki-67 expression with cell proliferation, anti-Ki-67 antibodies are useful for the identification, quantification, and monitoring of growing cell populations.
Specifications
| Ki-67 | |
| B56 | |
| Mouse | |
| RUO | |
| Human |
| Flow Cytometry | |
| RY586 | |
| 100 Tests | |
| Primary |
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