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  6. BD Horizon™ Ki-67 Mouse, anti-Human, RY586, Clone: B56, BD Horizon™

BD Horizon™ Ki-67 Mouse, anti-Human, RY586, Clone: B56, BD Horizon™

Catalog No. BDB568148 Shop All BD Biosciences Products
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BDB568148 25 Tests
BDB568147 100 Tests
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Catalog No. BDB568148 Supplier BD Horizon™ Supplier No. 568148
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Description

Mouse Monoclonal Antibody

The B56 monoclonal antibody specifically binds to the Ki-67 antigen that is expressed in the nucleus of cycling cells (G1, S, G2, M cell cycle phases). During the G0 phase, the antigen cannot be detected. During interphase of the cell cycle, it is associated with nucleolar components, and it is on the surface of the chromosomes during M phase. Ki-67 is a large protein having 2 alternatively spliced isoforms, an N-terminal forkhead-associated domain, a C-terminal domain that binds to heterochromatin proteins, and multiple phosphorylation sites, the functions of which are still unclear. Because of the strict association of Ki-67 expression with cell proliferation, anti-Ki-67 antibodies are useful for the identification, quantification, and monitoring of growing cell populations.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Ki-67
Applications Flow Cytometry
Clone B56
Conjugate RY586
Host Species Mouse
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
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