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Ki-67 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

$151.31 - $568.26

Specifications

Antigen Ki-67
Applications Immunofluorescence, Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Form Liquid
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-157-2022
Encompass_Preferred
View Documents
Bethyl Laboratories, Inc
IHC00395T
10 μL
Each for $151.31
Only null left
Add to Cart
 
50-157-2021
Encompass_Preferred
View Documents
Bethyl Laboratories, Inc
IHC00395
100 μL
Each for $568.26
Only null left
Add to Cart
 
Description

Description

The recommended shelf life for this product is 1 year from date of receipt.

Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.
Specifications

Specifications

Ki-67
Polyclonal
Liquid
RUO
TBS with 0.1% BSA and 0.09% sodium azide
antigen identified by monoclonal antibody Ki-67, KIA, MIB-, MIB-1, PPP1R105, proliferation-related Ki-67 antigen, protein phosphatase 1, regulatory subunit 105
MKI67
IgG
Antigen affinity chromatography
Antibody
Immunofluorescence, Immunohistochemistry
Unconjugated
Rabbit
Human
P46013
4288
Between 1800 and 1850
Primary
4° C
MKI67
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