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Ki-67 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
$151.31 - $568.26
Specifications
Antigen | Ki-67 |
---|---|
Applications | Immunofluorescence, Immunohistochemistry |
Classification | Polyclonal |
Conjugate | Unconjugated |
Form | Liquid |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-157-2022
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Bethyl Laboratories, Inc
IHC00395T |
10 μL |
Each for $151.31
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50-157-2021
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Bethyl Laboratories, Inc
IHC00395 |
100 μL |
Each for $568.26
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Description
The recommended shelf life for this product is 1 year from date of receipt.
Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.Specifications
Ki-67 | |
Polyclonal | |
Liquid | |
RUO | |
TBS with 0.1% BSA and 0.09% sodium azide | |
antigen identified by monoclonal antibody Ki-67, KIA, MIB-, MIB-1, PPP1R105, proliferation-related Ki-67 antigen, protein phosphatase 1, regulatory subunit 105 | |
MKI67 | |
IgG | |
Antigen affinity chromatography | |
Antibody |
Immunofluorescence, Immunohistochemistry | |
Unconjugated | |
Rabbit | |
Human | |
P46013 | |
4288 | |
Between 1800 and 1850 | |
Primary | |
4° C | |
MKI67 |
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