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Ki67 Mouse anti-Human, Clone: OTI3D11, liquid, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA500265

Encompass_Preferred

Catalog No. 50-167-1445


May include imposed supplier surcharges.
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Description

Description

Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.
Specifications

Specifications

Ki67
Monoclonal
Unconjugated
MKI67
KIA, MIB-, MIB-1, PPP1R105
Mouse
Affinity Chromatography
RUO
4288
-20° C, Avoid Freeze/Thaw Cycles
Liquid
Immunohistochemistry (Paraffin), Western Blot
OTI3D11
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P46013
MKI67
Recombit protein expressed in E.coli corresponding to amino acids 1-250 of human MKI67.
100 μL
Primary
Human
Antibody
IgG2b
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