KIAA0141 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-3632	Proteintech Group Inc 219041AP150UL	150 μL

Description

DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-Alpha and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-Alpha, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.

Specifications

• Antigen: KIAA0141
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q14154, Q9DCV6
• Gene ID (Entrez): 66839, 9812
• Immunogen: KIAA0141 Fusion Protein Ag14615
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: KIAA0141

• Concentration: 0.36 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: KIAA0141
• Gene Symbols: Dele1, KIAA0141
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody