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Invitrogen™ KIAA0556 Polyclonal Antibody
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Catalog No. PIPA557152
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100 μL
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PIPA557152 100 μL
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Catalog No. PIPA557152 Supplier Invitrogen™ Supplier No. PA557152
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EPPVDYSDDF ELCGDVTLQA NNTSEDRPQE LRRSLELSVN LQRKQKDCSS DEYDSIEEDI LSEPEPEDPA LVGHPRHDRP PSSGDWTQKD VHGE Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 51%.

This gene encodes a novel, evolutionarily conserved, ciliary protein. In human hTERT-RPE1 cells, the protein is found at the base of cilia, decorating the ciliary axoneme, and enriched at the ciliary tip. The protein binds to microtubules in vitro and regulates their stability when it is overexpressed. A null mutation in this gene has been associated with Joubert syndrome, a recessive disorder that is characterized by a distinctive mid-hindbrain and cerebellar malformation and is also often associated with wider ciliopathy symptoms. Consistently, in a serum-starvation ciliogenesis assay, human fibroblast cells derived from patients with the mutation display a reduced number of ciliated cells with abnormally long cilia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KIAA0556
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene KIAA0556
Gene Accession No. O60303
Gene Alias JBTS26; Katanin-interacting protein; Katnip; KIAA0556; Protein KIAA0556
Gene Symbols KIAA0556
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human KIAA0556. Recombinant protein control fragment (Product #RP-94967).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23247
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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