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Invitrogen™ KIAA1530 Polyclonal Antibody
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Catalog No. PIPA565796
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100 μL
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PIPA565796 100 μL
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Catalog No. PIPA565796 Supplier Invitrogen™ Supplier No. PA565796
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Rabbit Polyclonal Antibody

Immunogen sequence: RLSAFQIVEEL FVRSHQFRML VVSNFQEFLE LTLGTDPAQP LPPPREAAQR LRQATTRAVE GWNEKFGEAY KKLALGYHFL RHNKKVDFQD TNARSL Highest antigen sequence identity to the following orthologs - mouse 81%, rat 82%.

The protein encoded by KIAA1530 appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in KIAA1530 can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KIAA1530
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene UVSSA
Gene Accession No. Q2YD98
Gene Alias KIAA1530; UV stimulated scaffold protein A; UVSS3; UVSSA; UV-stimulated scaffold protein A
Gene Symbols UVSSA
Host Species Rabbit
Immunogen Recombinant Human KIAA1530. Recombinant protein control fragment (Product #RP-106469).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57654
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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