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KIBRA Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981481
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100 μL
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50-198-1481 100 μL
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Catalog No. 50-198-1481 Supplier Bioss Supplier No. BS11570R
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Description

Rabbit Polyclonal Antibody

WWC1 (Protein KIBRA) is a probable regulator of the Hippo/SWH signaling pathway. This pathway plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. WWC1, along with NF2, can synergistically induce the phosphorylation of LATS1 and LATS2. It acts as a transcriptional coactivator of ESR1 - which plays an essential role in DYNLL1-mediated ESR1 transactivation. WWC1 also functions as a regulatior of collagen-stimulated activation of the ERK/MAPK cascade.

Specifications

Antigen KIBRA
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene WWC1
Gene Accession No. Q8IX03
Gene Alias AA408228; AU017197; BC037006; FLJ10865; FLJ23369; HBeAg-binding protein 3; HBEBP3; HBEBP36; Kiaa0869; KIBRA; Kidney and brain protein; MEMRYQTL; mKIAA0869; PPP1R168; Protein KIBRA; protein phosphatase 1, regulatory subunit 168; protein WWC1; RGD1308329; WW and C2 domain containing 1; WW domain-containing protein 1; WW, C2 and coiled-coil domain containing 1; Wwc1
Gene Symbols WWC1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human KIBRA.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23286
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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