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Invitrogen™ KIDINS220 Polyclonal Antibody
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Catalog No. PIPA582511
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100 μL
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PIPA582511 100 μL
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Catalog No. PIPA582511 Supplier Invitrogen™ Supplier No. PA582511
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EPLLEIDGDI RNFEVFLSSR TPVLVARDVK VFLPCTVNLD PKLREIIADV RAAREQISIG GLAYPPLPLH EGPPRAPSGY SQPPSVCSST SFNGPFAGGV VS Highest antigen sequence indentity to the following orthologs: Rat - 94%, Mouse - 92%.

This gene encodes a transmembrane protein that is preferentially expressed in the nervous system where it controls neuronal cell survival, differentiation into exons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, serving as a scaffold that mediates crosstalk between the neurotrophin pathway and several other intracellular signaling pathways. Aberrant expression of this gene is associated with the onset of various neuropsychiatric disorders and neurodegenerative diseases, including Alzheimer's disease. Naturally occurring mutations in this gene are associated with a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus and obesity. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KIDINS220
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Kidins220
Gene Accession No. Q9ULH0
Gene Alias 3110039L19Rik; AI194387; AI316525; ankyrin repeat-rich membrane spanning; ankyrin repeat-rich membrane spanning protein; ankyrin repeat-rich membrane-spanning protein; ARMS; C330002I19Rik; KIAA1250; KIDINS220; kinase D-interacting substance 220; kinase D-interacting substance of 220 kDa; kinase D-interacting substrate 220; kinase D-interacting substrate 220kDa; kinase D-interacting substrate of 220 kDa; kinase D-interacting substrate, 220kDa; MGC163482; mKIAA1250; truncated KIDINS220
Gene Symbols Kidins220
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human KIDINS220. Recombinant protein control fragment (Product #RP-91147).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57498
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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