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Invitrogen™ KIF14 Polyclonal Antibody
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Catalog No. PIPA584368
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100 μL
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PIPA584368 100 μL
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Catalog No. PIPA584368 Supplier Invitrogen™ Supplier No. PA584368
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MKLSMMIQEA NAISSKLKTY YVFGRHDISD KSSSDTSIRV RNLKLGISTF WSLEKFESKL AAMKELYESN GSNRGEDA Highest antigen sequence indentity to the following orthologs: Rat - 59%, Mouse - 81%.

This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. In human HeLa-S3 and 293T cells, this protein is localized to the cytoplasm during interphase, to the spindle poles and spindle microtubules during mitosis, and to the midbody during cytokinesis. An internal motor domain displays microtubule-dependent ATPase activity, consistent with its function as a microtubule motor protein. Knockdown of this gene results in failed cytokinesis with endoreplication, which results in multinucleated cells. This gene has been identified as a likely oncogene in breast, lung and ovarian cancers, as well as retinoblastomas and gliomas. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KIF14
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene KIF14
Gene Accession No. Q15058
Gene Alias D1Ertd367e; E130203M01; KIAA0042; KIF14; kinesin family member 14; kinesin-like protein KIF14; MKS12; N-3 kinesin; truncated kinesin family member 14
Gene Symbols KIF14
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human KIF14. Recombinant protein control fragment (Product #RP-106832).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9928
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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