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Invitrogen™ KIF24 Polyclonal Antibody
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Catalog No. PIPA525624
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400 μL
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Catalog No. Quantity
PIPA525624 400 μL
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Catalog No. PIPA525624 Supplier Invitrogen™ Supplier No. PA525624
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Description

Rabbit Polyclonal Antibody

KIF24 Polyclonal Antibody for Western Blot, IHC (P), Flow

Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation. Following activation by NEK2 involved in disassembly of primary cilium during G2/M phase but does not disassemble fully formed ciliary axonemes. As cilium assembly and disassembly is proposed to coexist in a dynamic equilibrium may suppress nascent cilium assembly and, potentially, ciliar re-assembly in cells that have already disassembled their cilia ensuring the completion of cilium removal in the later stages of the cell cycle. Plays an important role in recruiting MPHOSPH9, a negative regulator of cilia formation to the distal end of mother centriole.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KIF24
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene KIF24
Gene Accession No. Q5T7B8, Q6NWW5
Gene Alias 4933425J19Rik; 9430029L23Rik; bA571F15.4; C9orf48; KIF24; kinesin family member 24; kinesin-like protein KIF24
Gene Symbols KIF24
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 356-384 amino acids from the N-terminal region of human KIF24.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 109242, 347240
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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