Invitrogen™ KIFC2 Polyclonal Antibody

Catalog No.	Quantity
PIPA556098	100 μL

Catalog No. PIPA556098 Supplier Invitrogen™ Supplier No. PA556098

Description

Rabbit Polyclonal Antibody

Immunogen sequence: QLILGQLEEL KQQLEQQEEE LGRLRLGVGA TDSEKRVQHL TLENEALKQS LSLMRDLLLH WGPGPPIRAP QEEAEALLEL QGRLQEAQDT TEALRAQ Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.

Kinesins are a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure which includes a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain. An expansive phylogenetic tree of kinesins and kinesin-related proteins (KRPs) has been assembled based on this information. Kinesin C2 (KIFC2) is a C-type kinesin based on the position of the motor domain towards the carboxyl-terminus of the protein and is similar to members of the karyogamy protein 3 (KAR3) family involved in cell division. KIFC2 protein expression has been demonstrated in axons and dendrites of the central and peripheral nervous system. Unlike other C-type motor proteins, KIFC2 appears to play a role in retrograde axonal transport.

Specifications

• Antigen: KIFC2
• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.7 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: Kifc2
• Gene Accession No.: Q96AC6
• Gene Alias: KIFC2; kinesin family member C2; kinesin-like protein KIFC2
• Gene Symbols: Kifc2
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human KIFC2. Recombinant protein control fragment (Product #RP-93887).
• Purification Method: Antigen Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 90990
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG