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Invitrogen™ Kinesin 5B Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA119392
Description
This antibody detects total level of endogenous kinesin protein (intracellular antigen).
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.
Specifications
Kinesin 5B | |
Polyclonal | |
Unconjugated | |
KIF5B | |
AL022807; Conventional kinesin heavy chain; EMBL:ABC25059.1}; epididymis secretory protein Li 61; HEL-S-61; Khc; Khcs; KIF5A; KIF5B; kif5b {ECO:0000312; kinesin 1 (110-120kD); kinesin family member 5A; kinesin family member 5B; kinesin heavy chain; kinesin heavy chain member 5B, ubiquitous; kinesin-1 heavy chain; KINH; KNS; Kns1; ubiquitous kinesin heavy chain; UKHC; U-KHC; Unknown (protein for IMAGE:7944745) | |
Rabbit | |
Affinity chromatography | |
RUO | |
16573, 3799, 595132 | |
4°C, do not freeze | |
Liquid |
Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 15 mM sodium azide; pH 7.4 | |
P33176, Q61768 | |
KIF5B | |
Stalk domain of human kinesin, expressed in (aa 331-906) E. coli. | |
100 μg | |
Primary | |
Human, Mouse, Pig | |
Antibody | |
IgG |
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