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Invitrogen™ Kinesin 5B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA119392

Catalog No. 01-676-753


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Description

Description

This antibody detects total level of endogenous kinesin protein (intracellular antigen).

Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Kinesin 5B
Polyclonal
Unconjugated
KIF5B
AL022807; Conventional kinesin heavy chain; EMBL:ABC25059.1}; epididymis secretory protein Li 61; HEL-S-61; Khc; Khcs; KIF5A; KIF5B; kif5b {ECO:0000312; kinesin 1 (110-120kD); kinesin family member 5A; kinesin family member 5B; kinesin heavy chain; kinesin heavy chain member 5B, ubiquitous; kinesin-1 heavy chain; KINH; KNS; Kns1; ubiquitous kinesin heavy chain; UKHC; U-KHC; Unknown (protein for IMAGE:7944745)
Rabbit
Affinity chromatography
RUO
16573, 3799, 595132
4°C, do not freeze
Liquid
Western Blot, Immunocytochemistry
1 mg/mL
PBS with 15 mM sodium azide; pH 7.4
P33176, Q61768
KIF5B
Stalk domain of human kinesin, expressed in (aa 331-906) E. coli.
100 μg
Primary
Human, Mouse, Pig
Antibody
IgG
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