Invitrogen™ Kinesin 5B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA119392

Catalog No. 01-676-753

Description

This antibody detects total level of endogenous kinesin protein (intracellular antigen).

Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.

Specifications

• Antigen: Kinesin 5B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KIF5B
• Gene Alias: AL022807; Conventional kinesin heavy chain; EMBL:ABC25059.1}; epididymis secretory protein Li 61; HEL-S-61; Khc; Khcs; KIF5A; KIF5B; kif5b {ECO:0000312; kinesin 1 (110-120kD); kinesin family member 5A; kinesin family member 5B; kinesin heavy chain; kinesin heavy chain member 5B, ubiquitous; kinesin-1 heavy chain; KINH; KNS; Kns1; ubiquitous kinesin heavy chain; UKHC; U-KHC; Unknown (protein for IMAGE:7944745)
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16573, 3799, 595132
• Content And Storage: 4°C, do not freeze
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 15 mM sodium azide; pH 7.4
• Gene Accession No.: P33176, Q61768
• Gene Symbols: KIF5B
• Immunogen: Stalk domain of human kinesin, expressed in (aa 331-906) E. coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Pig
• Product Type: Antibody
• Isotype: IgG