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Invitrogen™ Kininogen 1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA581957
Description
Immunogen sequence: ALKKYNSQNQ SNNQFVLYRI TEATKTVGSD TFYSFKYEIK EGDCPVQSGK TWQDCEYKDA AKAATGECTA TVGKRSSTKF SVATQTCQIT PAEGPVVTAQ YDCLGCVHPI STQSPDLEPI LRHGIQYFNN N.
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
Specifications
Kininogen 1 | |
Polyclonal | |
Unconjugated | |
KNG1 | |
alpha-1-MAP; Alpha-2-thiol proteinase inhibitor; BDK; BK; Bradykinin; fitzgerald factor; high molecular weight kininogen; H-kininigen; HMWK; Ile-Ser-Bradykinin; Kallidin I; Kallidin II; kininogen; kininogen 1; kininogen 1-like 1; kininogen-1; Kininogen-1 heavy chain; Kininogen-1 light chain; Kng; Kng1; Kng1l1; L-kininogen; low molecular weight (LMW) T-kininogen II; Low molecular weight growth-promoting factor; Lysyl-bradykinin; Major acute phase protein; major acute phase protein (alpha-1-MAP); Thiostatin; T-kinin; T-kininogen 2; T-kininogen 2 heavy chain; T-kininogen 2 light chain; T-kininogen II; T-kininogen II heavy chain; T-kininogen II light chain; williams-Fitzgerald-Flaujeac factor | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
3827 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
P01042 | |
KNG1 | |
Recombinant protein corresponding to Human KNG1. Recombinant protein control fragment (Product #RP-100525). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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