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Invitrogen™ Kininogen 1 Polyclonal Antibody
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Catalog No. PIPA581961
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100 μL
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PIPA581961 100 μL
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Catalog No. PIPA581961 Supplier Invitrogen™ Supplier No. PA581961
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LFLTPDCKSL WNGDTGECTD NAYIDIQLRI ASFSQNCDIY PGKDFVQPPT KICVGCPRDI PTNSPELEET LTHTITKLNA ENNATFYFKI DNVKKARVQV VAGKKYFIDF VARETTCSKE SNEELTESCE TK Highest antigen sequence indentity to the following orthologs: Mouse - 59%, Rat - 58%.

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Kininogen 1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene KNG1
Gene Accession No. P01042
Gene Alias alpha-1-MAP; Alpha-2-thiol proteinase inhibitor; BDK; BK; Bradykinin; fitzgerald factor; high molecular weight kininogen; H-kininigen; HMWK; Ile-Ser-Bradykinin; Kallidin I; Kallidin II; kininogen; kininogen 1; kininogen 1-like 1; kininogen-1; Kininogen-1 heavy chain; Kininogen-1 light chain; Kng; Kng1; Kng1l1; L-kininogen; low molecular weight (LMW) T-kininogen II; Low molecular weight growth-promoting factor; Lysyl-bradykinin; Major acute phase protein; major acute phase protein (alpha-1-MAP); Thiostatin; T-kinin; T-kininogen 2; T-kininogen 2 heavy chain; T-kininogen 2 light chain; T-kininogen II; T-kininogen II heavy chain; T-kininogen II light chain; williams-Fitzgerald-Flaujeac factor
Gene Symbols KNG1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human KNG1. Recombinant protein control fragment (Product #RP-100524).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3827
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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