Invitrogen™ Kininogen Light Chain Monoclonal Antibody (C11C1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA110831

Catalog No. 01-671-859

Description

MA1-10831 detects High MW Kininogen, light chain, from human samples. MA1-10831 has been successfully used in ELISA and Western blot applications. The MA1-10831 immunogen is purified high molecular weight kininogen.

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Kininogen Light Chain
• Classification: Monoclonal
• Concentration: 0.9 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P01042
• Gene Symbols: KNG1
• Immunogen: Purified high molecular weight kininogen.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot
• Clone: C11C1
• Conjugate: Unconjugated
• Gene: KNG1
• Gene Alias: alpha-1-MAP; Alpha-2-thiol proteinase inhibitor; BDK; BK; bradykinin; Fitzgerald factor; high molecular weight kininogen; H-kininigen; HMWK; Ile-Ser-Bradykinin; Kallidin I; Kallidin II; kininogen; kininogen 1; kininogen 1-like 1; kininogen-1; Kininogen-1 heavy chain; Kininogen-1 light chain; KNG; KNG1; Kng1l1; L-kininogen; low molecular weight (LMW) T-kininogen II; Low molecular weight growth-promoting factor; Lysyl-bradykinin; Major acute phase protein; major acute phase protein (alpha-1-MAP); Thiostatin; T-kinin; T-kininogen 2; T-kininogen 2 heavy chain; T-kininogen 2 light chain; T-kininogen II; T-kininogen II heavy chain; T-kininogen II light chain; williams-Fitzgerald-Flaujeac factor
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 3827
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid