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Invitrogen™ KIP2 Polyclonal Antibody
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Catalog No. PA549772
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100 μL
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PA549772 100 μL
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Catalog No. PA549772 Supplier Invitrogen™ Supplier No. PA549772
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total KIP2 protein.

DNA-dependent protein kinases (DNA-PK) play a role in the repair of double-strand DNA breaks and in the process of V(D)J recombination during lymphoid development. By EST database searching for sequences homologous to the DNA-PK gene KIP/CIB and 5-prime RACE, Seki, N et al. isolated a full-length cDNA, which they designated as KIP2, from a human fetal brain cDNA library. KIP2 encodes a deduced 187-amino acid protein with a predicted molecular mass of 22 kD. The KIP2 protein shares 46%, 39%, and 30% sequence identity with the calcium-binding proteins KIP/CIB, calcineurin B and calmodulin respectively. KIP2 contains two EF-hand motifs and a helix-loop-helix motif involved in coordinating the calcium ion, indicating that KIP2 may also bind calcium. KIP2 is ubiquitously expressed in various human tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KIP2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CIB2
Gene Accession No. O75838, Q9Z309
Gene Alias 2810434I23Rik; AI449053; calcium and integrin binding family member 2; calcium and integrin-binding family member 2; calcium binding protein Kip 2; calcium binding protein Kip2; CIB2; DFNB48; DNA-dependent protein kinase catalytic subunit-interacting protein 2; kinase interacting protein 2; kinase-interacting protein 2; KIP 2; Kip2; USH1J
Gene Symbols CIB2
Host Species Rabbit
Immunogen Synthesized peptide derived from internal of human CIB2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10518, 56506
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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