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Invitrogen™ KIP2 Polyclonal Antibody
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Catalog No. PIPA5104486
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PIPA5104486 100 μL
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Catalog No. PIPA5104486 Supplier Invitrogen™ Supplier No. PA5104486
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CIB2.

DNA-dependent protein kinases (DNA-PK) play a role in the repair of double-strand DNA breaks and in the process of V(D)J recombination during lymphoid development. By EST database searching for sequences homologous to the DNA-PK gene KIP/CIB and 5-prime RACE, Seki, N et al. isolated a full-length cDNA, which they designated as KIP2, from a human fetal brain cDNA library. KIP2 encodes a deduced 187-amino acid protein with a predicted molecular mass of 22 kD. The KIP2 protein shares 46%, 39%, and 30% sequence identity with the calcium-binding proteins KIP/CIB, calcineurin B and calmodulin respectively. KIP2 contains two EF-hand motifs and a helix-loop-helix motif involved in coordinating the calcium ion, indicating that KIP2 may also bind calcium. KIP2 is ubiquitously expressed in various human tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KIP2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CIB2
Gene Accession No. O75838, Q568Z7, Q9Z309
Gene Alias 2810434I23Rik; AI449053; calcium and integrin binding family member 2; calcium and integrin-binding family member 2; calcium binding protein Kip 2; calcium binding protein Kip2; CIB2; DFNB48; DNA-dependent protein kinase catalytic subunit-interacting protein 2; kinase interacting protein 2; kinase-interacting protein 2; KIP 2; Kip2; USH1J
Gene Symbols CIB2
Host Species Rabbit
Immunogen A synthesized peptide derived from human CIB2(Accession O75838), corresponding to amino acid residues N40-D90.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10518, 300719, 56506
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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