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Invitrogen™ Kir1.1 (KCNJ1) Polyclonal Antibody
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Catalog No. PIPA582946
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100 μL
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PIPA582946 100 μL
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Catalog No. PIPA582946 Supplier Invitrogen™ Supplier No. PA582946
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Rabbit Polyclonal Antibody

Immunogen sequence: STSATCQVRT SYVPEEVLWG YRFAPIVSKT KEGKYRVDFH NFSKTVEVET PHCAMCLYNE KDVRARMKRG YDNPNFILSE VNETD Highest antigen sequence indentity to the following orthologs: Rat - 94%, Mouse - 93%.

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Kir1.1 (KCNJ1)
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene KCNJ1
Gene Accession No. P48048
Gene Alias ATP-regulated potassium channel ROM-K; ATP-sensitive inward rectifier potassium channel 1; inward rectifier K(+) channel Kir1.1; inwardly rectifying K+ channel; inwardly rectifying potassium channel ROMK-2; K+ channel protein; KAB-1; Kcnj; Kcnj1; KIR1.1; LOW QUALITY PROTEIN: ATP-sensitive inward rectifier potassium channel 1; OTTHUMP00000045938; potassium channel, inwardly rectifying subfamily J member 1; potassium channel, inwardly rectifying subfamily J, member 1; potassium inwardly rectifying channel subfamily J member 1; potassium inwardly-rectifying channel J1; Potassium inwardly-rectifying channel subfamily J; potassium inwardly-rectifying channel, subfamily J, member 1; potassium voltage-gated channel subfamily J member 1; ROMK; ROMK1; Romk2
Gene Symbols KCNJ1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human KCNJ1. Recombinant protein control fragment (Product #RP-90994).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3758
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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