Invitrogen™ Kir1.1 (KCNJ1) Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA519072

Catalog No. PIPA519072

Description

This antibody is predicted to react with mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Kir1.1 (KCNJ1)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNJ1
• Gene Alias: ATP-regulated potassium channel ROM-K; ATP-sensitive inward rectifier potassium channel 1; inward rectifier K(+) channel Kir1.1; inwardly rectifying K+ channel; inwardly rectifying potassium channel ROMK-2; K+ channel protein; KAB-1; Kcnj; Kcnj1; KIR1.1; LOW QUALITY PROTEIN: ATP-sensitive inward rectifier potassium channel 1; OTTHUMP00000045938; potassium channel, inwardly rectifying subfamily J member 1; potassium channel, inwardly rectifying subfamily J, member 1; potassium inwardly rectifying channel subfamily J member 1; potassium inwardly-rectifying channel J1; Potassium inwardly-rectifying channel subfamily J; potassium inwardly-rectifying channel, subfamily J, member 1; potassium voltage-gated channel subfamily J member 1; ROMK; ROMK1; Romk2
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 3758
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P48048
• Gene Symbols: KCNJ1
• Immunogen: Synthetic peptide sequence (DQININFVVDAGNEN ) corresponding to the internal amino acids of KCNJ1 (aa 245-259).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG