Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ Kir2.1 (KCNJ2) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588883

Catalog No. PIPA588883


Only null left
Add to Cart

Description

Description

Immunogen sequence: NEILWGHRYE PVLFEEKHYY KVDYSRFHKT YEVPNTPLCS ARDLAEKKYI LSNANSFCYE NEVALTSKEE DDSENGVPES TSTDTPPDID LHNQASVPLE PRPLRRESEI; Positive Samples: A-549, Mouse heart, Rat heart; Cellular Location: Lipid-anchor, Membrane, Multi-pass membrane protein.

The KIR2 subunit family includes 2. 1, 2. 2, 2. 3 and 2. 4. Unlike G protein-coupled KIR3 subunits, KIR2. 1 requires both phosphorylation by PKA and ATP hydrolysis for functional activity. KIR2. 1 is expressed in the superior and inferior collicula and the pontine region of the brain, where it moderates synaptic transmission, like many other potassium channels. In the placenta, KIR2. 1 is expressed throughout gestation in cytotrophoblast cells. In the kidney, KIR2. 1 colocalizes with KIR5. 1 in the proximal tubule. KIR2. 1, 2. 2 and 2. 3 associate with the membrane-associated guanylate kinase synapseassociated protein 97 in the cerebellum and heart. Phosphorylation of KIR2. 2 by protein kinase A inhibits the associates with SAP97.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Kir2.1 (KCNJ2)
Polyclonal
Unconjugated
Kcnj2
ATFB9; cardiac inward rectifier KIR2.1; cardiac inward rectifier potassium channel; EGK_08925; HHBIRK1; HHIRK 1; HHIRK1; HIRK 1; hIRK1; Inward rectifier K; inward rectifier K(+) channel Kir2.1; inward rectifier K+ channel KIR2.1; inward rectifier potassium channel; inward rectifier potassium channel 2; inwardly rectifying potassium channel Kir2.1; IRK 1; IRK1; IRK-1; IRK2; Kcnf1; KCNJ2; KIR2.1; LQT 7; LQT7; Potassium channel, inwardly rectifying subfamily J member 2; potassium channel, inwardly rectifying subfamily J, member 2; potassium inwardly rectifying channel subfamily J member 2; potassium inwardly-rectifying channel, subfamily J, member 2; potassium voltage-gated channel subfamily J member 2; RBL-IRK1; SQT 3; SQT3
Rabbit
Affinity Chromatography
RUO
16518, 29712, 3759
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Immunohistochemistry (Paraffin), Western Blot
1.72 mg/mL
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
P35561, P63252, Q64273
Kcnj2
Recombinant fusion protein containing a sequence corresponding to amino acids 318-427 of human KCNJ2 (NP_0008821).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
Safety and Handling

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.