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Invitrogen™ Kir2.1 (KCNJ2) Recombinant Rabbit Monoclonal Antibody (JE54-56)
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Catalog No. FEMA550748
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FEMA550748 100 μL
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Catalog No. FEMA550748 Supplier Invitrogen™ Supplier No. MA550748
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Description

Rabbit Recombinant Monoclonal Antibody

Positive control: N2A, SW620, rat uterus tissue, human placenta tissue, mouse brain tissue. Predicted band size: 48 kDa Subcellular Location: Membrane.

The KIR2 subunit family includes 2. 1, 2. 2, 2. 3 and 2. 4. Unlike G protein-coupled KIR3 subunits, KIR2. 1 requires both phosphorylation by PKA and ATP hydrolysis for functional activity. KIR2. 1 is expressed in the superior and inferior collicula and the pontine region of the brain, where it moderates synaptic transmission, like many other potassium channels. In the placenta, KIR2. 1 is expressed throughout gestation in cytotrophoblast cells. In the kidney, KIR2. 1 colocalizes with KIR5. 1 in the proximal tubule. KIR2. 1, 2. 2 and 2. 3 associate with the membrane-associated guanylate kinase synapseassociated protein 97 in the cerebellum and heart. Phosphorylation of KIR2. 2 by protein kinase A inhibits the associates with SAP97.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Kir2.1 (KCNJ2)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone JE54-56
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 1% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Kcnj2
Gene Accession No. P35561, P63252, Q64273
Gene Alias ATFB9; cardiac inward rectifier KIR2.1; cardiac inward rectifier potassium channel; EGK_08925; HHBIRK1; HHIRK 1; HHIRK1; HIRK 1; hIRK1; Inward rectifier K; inward rectifier K(+) channel Kir2.1; inward rectifier K+ channel KIR2.1; inward rectifier potassium channel; inward rectifier potassium channel 2; inwardly rectifying potassium channel Kir2.1; IRK 1; IRK1; IRK-1; IRK2; Kcnf1; KCNJ2; KIR2.1; LQT 7; LQT7; Potassium channel, inwardly rectifying subfamily J member 2; potassium channel, inwardly rectifying subfamily J, member 2; potassium inwardly rectifying channel subfamily J member 2; potassium inwardly-rectifying channel, subfamily J, member 2; potassium voltage-gated channel subfamily J member 2; RBL-IRK1; SQT 3; SQT3
Gene Symbols Kcnj2
Host Species Rabbit
Immunogen Synthetic peptide within Human Kir2.1 aa 91-140/427.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16518, 29712, 3759
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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