Invitrogen™ Kir2.2 (KCNJ12) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA568685

Catalog No. PIPA568685

Description

This target displays homology in the following species: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%.

Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Specifications

• Antigen: Kir2.2 (KCNJ12)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Kcnj12
• Gene Alias: ATP-sensitive inward rectifier potassium channel 12; atrium potassium channel IRK; DirK; hIRK; hIRK1; hkir2.2x; Inward rectifier K(+) channel Kir2.2; inward rectifier K(+) channel Kir2.2v; inward rectifier K(+) channel Kir2.6; inward rectifier potassium channel Kir2.2; inwardly-rectifying potassium channel KCNJ12; inwardly-rectifying potassium channel Kir2.2; IRK; Irk2; IRK-2; KCNJ12; kcnj12x; KCNJN1; Kir2.1; Kir2.2; Kir2.2v; MB-IRK2; potassium channel, inwardly rectifying subfamily J member 12; potassium channel, inwardly rectifying subfamily J, member 12; potassium inwardly rectifying channel subfamily J member 12; potassium inwardly-rectifying channel J12; potassium inwardly-rectifying channel, subfamily J, inhibitor 1; potassium inwardly-rectifying channel, subfamily J, member 12; potassium voltage-gated channel subfamily J member 12; subfamily J, member 12
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3768
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q14500
• Gene Symbols: Kcnj12
• Immunogen: synthetic peptide directed towards the middle region of human KCNJ12.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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