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Invitrogen™ Kir2.2 (KCNJ12) Polyclonal Antibody
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Catalog No. PIPA5116581
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100 μL
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PIPA5116581 100 μL
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Catalog No. PIPA5116581 Supplier Invitrogen™ Supplier No. PA5116581
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Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse brain, Rat brain Immunogen sequence: TPRCSAKDLV ENKFLLPSAN SFCYENELAF LSRDEEDEAD GDQDGRSRDG LSPQARHDFD RLQAGGGVLE QRPYRRESEI.

Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Kir2.2 (KCNJ12)
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.74 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Kcnj12
Gene Accession No. P52187, P52188
Gene Alias ATP-sensitive inward rectifier potassium channel 12; atrium potassium channel IRK; DirK; hIRK; hIRK1; hkir2.2x; Inward rectifier K(+) channel Kir2.2; inward rectifier K(+) channel Kir2.2v; inward rectifier K(+) channel Kir2.6; inward rectifier potassium channel Kir2.2; inwardly-rectifying potassium channel KCNJ12; inwardly-rectifying potassium channel Kir2.2; IRK; Irk2; IRK-2; KCNJ12; kcnj12x; KCNJN1; Kir2.1; Kir2.2; Kir2.2v; MB-IRK2; potassium channel, inwardly rectifying subfamily J member 12; potassium channel, inwardly rectifying subfamily J, member 12; potassium inwardly rectifying channel subfamily J member 12; potassium inwardly-rectifying channel J12; potassium inwardly-rectifying channel, subfamily J, inhibitor 1; potassium inwardly-rectifying channel, subfamily J, member 12; potassium voltage-gated channel subfamily J member 12; subfamily J, member 12
Gene Symbols Kcnj12
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 354-433 of human KCNJ12 (NP_0662922).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117052, 16515
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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