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Invitrogen™ KIR2DL3 Polyclonal Antibody
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Catalog No. PIPA576046
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PIPA576046 100 μL
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Catalog No. PIPA576046 Supplier Invitrogen™ Supplier No. PA576046
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

NKAT (NK-associated transcripts) gene products, known as killer immuno-globulin-like receptors or KIRs, downregulate the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells. This family of receptors is characterized by an extracellular region with two to three immunoglobulin-superfamily domains and a cytoplasmic domain with an antigen receptor activation motif (ARAM). KIRs and other inhibitory receptors also possess a common cytoplasmic sequence (I/VxYxxL/V) known as an ITIM (immunoreceptor tyrosine-based inhibitory motif). The human inhibitory human killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3), also referred to as CD158b, is an inhibitory receptor that is specific for the human MHC class I molecule HLA-Cw3 and related alleles.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KIR2DL3
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene KIR2DL3
Gene Accession No. P43628
Gene Alias CD158 antigen-like family member B2; CD158b; CD158B2; CU464054.1; GL183; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3; killer cell immunoglobulin-like receptor 2DL3; killer cell immunoglobulin-like receptor two domains long cytoplasmic tail 3; killer cell immunoglobulin-like receptor two domains short cytoplasmic tail 3; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3; killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5; killer Ig-like inhibitory receptor; killer inhibitory receptor cl 2-3; KIR-023GB; KIR2DL3; KIR2DS3; KIR2DS5; KIRCL23; KIR-K7b; KIR-K7c; MGC129943; MHC class I NK cell receptor; natural killer associated transcript 2; natural killer cell inhibitory receptor KIR2DL3; natural killer cell receptor; natural killer-associated transcript 2; NKAT; NKAT2; NKAT-2; NKAT2A; NKAT2B; NK-receptor; p58; p58 natural killer cell receptor clone CL-6; p58 NK receptor CL-6; p58.2 MHC class-I specific NK receptor; p58.2 MHC class-I-specific NK receptor
Gene Symbols KIR2DL3
Host Species Rabbit
Immunogen Recombinant full length Human KIR2DL3.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3804
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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