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Invitrogen™ KIR2DL4 Polyclonal Antibody

Catalog No. PIPA528190
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100 μL
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Catalog No. Quantity
PIPA528190 100 μL
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Catalog No. PIPA528190 Supplier Invitrogen™ Supplier No. PA528190

Description

Rabbit Polyclonal Antibody

Recommended positive controls: THP-1. Predicted reactivity: Rhesus Monkey (89%), Chimpanzee (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM, suggesting inhibitory function, but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells, but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-gamma secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KIR2DL4
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.9 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene KIR2DL4
Gene Accession No. Q99706
Gene Alias CD158 antigen-like family member D; CD158D; G9P; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4; killer cell immunoglobulin-like receptor 2DL4; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4; killer cell inhibitory receptor 103AS; killer Ig receptor; killer-cell immunoglobulin-like receptor; killer-cell immunoglobulin-like receptor 2DL4; KIR; KIR103; KIR103AS; KIR-103AS; KIR2DL4; KIR-2DL4; MHC class I NK cell receptor KIR103AS; natural killer cell inhibitory receptor; natural killer cell receptor; NK cell receptor
Gene Symbols KIR2DL4
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the Extracellular domain of human KIR2DL4. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3805
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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